The Ministry of Food and Drug Safety approved Sanofi-Aventis Korea's rare and new drug for cold agglutinin disease treatment, 'Nzyomo (Sutimlimab),' on the 12th.


Mechanism of action of NJM. [Provided by Sanofi Aventis Korea]

Mechanism of action of NJM. [Provided by Sanofi Aventis Korea]

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This drug is used for the treatment of hemolysis in adult patients with cold agglutinin disease, a type of autoimmune hemolytic anemia (AIHA) in which red blood cells agglutinate and cause hemolysis at temperatures below normal body temperature.



Nzyomo is an IgG4 monoclonal antibody (mAb) that binds to the complement (a protein or glycoprotein in serum acting on the immune system) protein C1s, inhibiting the activation process of the complement and thereby suppressing hemolysis.


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