LG Chem announced on the 30th that a long-term safety evaluation paper on the hyaluronic acid (HA) filler Y Solution has been published in Dermatologic Surgery, an SCI-level international dermatology journal.


LG Chem's hyaluronic acid filler 'Y Solution' <br>Photo by LG Chem

LG Chem's hyaluronic acid filler 'Y Solution'
Photo by LG Chem

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The large-scale observational study led by Professor Kwangho Yoo's research team from the Department of Dermatology at Chung-Ang University Medical Center was conducted on 1,022 subjects across nine domestic institutions including Chung-Ang University Medical Center. The researchers observed delayed nodules and adverse reactions that could occur after two weeks post-procedure for about one year following Y Solution treatment.


LG Chem explained that the study results confirmed Y Solution’s excellent tolerability and long-term safety. Delayed nodules and delayed adverse reactions were reported as 0 cases and 1 case (skin hypersensitivity reaction at the treatment site), respectively, indicating that the frequency of “adverse reactions that cannot exclude causality with the product” was very rare. Additionally, three cases of “adverse events unrelated to the product” were reported.


The paper suggested that LG Chem’s ▲S-HICE crosslinking technology ▲high molecular weight hyaluronic acid ▲minimized foreign substance process, which minimize the amount of crosslinking agent used to achieve volume improvement effects, likely contributed to the low incidence of side effects in Y Solution.


Y Solution is LG Chem’s premium brand of Evear, launched domestically in 2018. It features higher elasticity and cohesiveness compared to the existing Evear. It can be used for facial wrinkle improvement and volume restoration, such as nasolabial folds or deeply sunken cheeks.



No Ji-hye, Executive Director of LG Chem’s Aesthetic Business Division, said, “We are pleased that the excellence of LG Chem’s filler technology, represented by the Y Solution brand, has been proven through this large-scale observational study. We will continue to provide reliable treatment solutions to medical professionals and customers worldwide who pursue healthy beauty.”


This content was produced with the assistance of AI translation services.

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