ZenenCell Obtains Japanese Patent for Functional Ingredient Improving Premenstrual Syndrome

ZennCell announced on the 13th that it has obtained a Japanese patent for a functional ingredient that improves premenstrual syndrome (PMS). This patent is for a "composition for improving premenstrual syndrome symptoms containing Gujeolcho extract," related to ZennCell’s natural material-based malt and Gujeolcho extract complex called "Freemensia."

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PMS is a condition experienced by more than one-third of women of reproductive age, with symptoms such as mild mental disorders, abdominal bloating, weight gain, breast tenderness, muscle tension, decreased concentration, and changes in appetite. It can hinder women's social activities, including difficulties in the workplace, prompting ongoing efforts in the medical field to alleviate it. However, due to the lack of appropriate treatments, antidepressants, anti-inflammatory analgesics, and oral contraceptives are mainly prescribed.

ZennCell has demonstrated through preclinical and human clinical trials that Freemensia normalizes prolactin (milk hormone) secretion by activating dopamine receptors, inhibits estrogen (female hormone) receptor activation, and effectively alleviates PMS symptoms, protects pituitary cells, and improves uterine inflammation.

In particular, in human clinical trials, the symptom relief score for premenstrual syndrome was -1.872 in the Freemensia intake group compared to -0.514 in the placebo group, showing a significant difference of more than three times (p-value 0.029).

A ZennCell representative stated, "This patented ingredient is a high-functionality material utilizing native Korean plants, and we are currently preparing for commercialization with domestic distributors. We have also filed patents in the United States and Europe," adding, "We will actively seek overseas expansion based on this patent."

ZennCell has already obtained two domestic patents for Freemensia in 2019 and 2021, and in May of this year, it received approval as an "individually recognized functional ingredient" from the Korean Ministry of Food and Drug Safety.

This content was produced with the assistance of AI translation services.