Successful Creation of Artificial 'Human Embryo' Without Sperm or Egg...No Related Laws, 'Controversy Expected'
The Speed of Scientific Advancement Outpaces Discussions
Research teams from the United States and the United Kingdom have succeeded for the first time in the world in creating a human synthetic embryo using only stem cells, without fertilization of sperm and egg. Although it is a scientific achievement, controversy is expected due to the lack of legal and ethical consensus.
On the 14th (local time), the British daily The Guardian reported that the research team led by Professor Magdalena Zernicka-Goetz from the California Institute of Technology in the US and the University of Cambridge in the UK revealed their research results on 'human synthetic embryos' at the annual meeting of the International Society for Stem Cell Research (ISSCR) held in Boston, USA.
The embryo model created this time is at the 'gastrulation' stage, just before the formation of basic body organs such as the brain and heart. The research team explained that this model slightly exceeds the developmental stage corresponding to 14 days of a naturally implanted embryo. The embryonic stem cells used in the experiment were donated by patients from infertility clinics.
Professor Zernicka-Goetz stated at the conference, "We can create a model similar to a human embryo through reprogramming of (embryonic stem) cells." The research team clarified that the purpose of the study is not the creation of life but to "identify why embryos sometimes fail to develop after fertilization and implantation and to prevent such losses." They described it as "a very important experiment to discover why pregnancies fail."
Previously, in August last year, the Weizmann Institute in Israel published research results in the scientific journal Cell showing that they created artificial embryos with early-stage brain, heart, and intestines using mouse stem cells, sparking competition and discussion about whether such research could be applied to human models. At that time, the dominant view was that "due to a lack of knowledge about human embryos, it would be difficult to create them immediately," but less than a year later, it has become a reality.
This occurred in the absence of any legislation regarding artificial embryos. The maximum period for culturing embryos in the laboratory is 14 days. The Guardian stated, "It is unlikely that these artificial embryos will develop into humans," adding, "Under current law, artificial embryos cannot be implanted into a human uterus, and even if implanted, the probability of developing beyond the early stages is low."
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It is also an assessment that the pace of scientific advancement has outpaced legal systems and bioethical discussions. The Guardian pointed out, "This research may provoke ethical and legal controversies and demonstrates that the rapid progress in life sciences is not being matched by legislation."
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