[Asia Economy Reporter Minwoo Lee] MedPacto announced on the 13th that it has obtained a patent for an "antibody or its antigen-binding fragment that specifically binds to BAG2 polypeptide or its fragment."


Through this patent, it was discovered that the BAG2 protein is secreted outside the cell via interaction with the protease cathepsin B during the carcinogenesis process, and it was confirmed that the loss of BAG2 protein completely suppresses tumor formation and lung metastasis in a breast cancer animal model.



MedPacto stated, "Using this patent, we are developing an antibody therapeutic (MA-B2) targeting various cancers, including breast cancer, in which BAG2 is overexpressed."


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