Jeonnam National University Hospital Research Professor Daesung Park Receives Best Award from Korean Society of Interventional Medical Devices

Research and Development of Non-Polymer Drug-Eluting Stents by the Cardiovascular Convergence Research Center

[Asia Economy Honam Reporting Headquarters Reporter Lee Gwan-woo] Research Professor Park Dae-sung of the Cardiovascular Convergence Research Center at Chonnam National University Hospital was honored with the Grand Prize at the Korean Society of Interventional Medical Devices.

According to Chonnam National University Hospital on the 4th, Research Professor Park was selected as the Grand Prize winner in the basic division at this year’s Korean Society of Interventional Medical Devices Autumn Academic Conference for his research titled “Non-polymer Tacrolimus Drug-Eluting Stent: Introduction of Nanopores Investigated by Femtosecond.”

The awarded research has been registered as a domestic patent and recently filed for a U.S. patent, and the award ceremony will be held at the autumn academic conference in Seoul on the 6th.

The research details an effect where a separate surface binding functional group introduction process, which could be used in the manufacturing process of non-polymer drug-eluting stents, is not introduced, yet tacrolimus drugs are strongly and stably bonded to the stent. Additionally, the total amount of drug is greater and the drug elution delay is superior.

The advantage of the non-polymer tacrolimus drug-eluting cardiovascular stent is that, because it does not use polymers, it minimizes inflammation around the blood vessels compared to conventional stents. After the drug is eluted, the surface exhibits superhydrophobic properties, reducing thrombus aggregation and preventing late stent thrombosis.

Moreover, tacrolimus, an immunosuppressant, reduces T-cell activation and shows significant anti-inflammatory effects, resulting in effective suppression of localized inflammation in blood vessels surrounding the stent after implantation.

Jung Myung-ho, director of the Cardiovascular Convergence Research Center at Chonnam National University Hospital, stated, “Research Professor Park Dae-sung’s research results have proven through continuous studies and animal experiments on non-polymer drug-eluting stents that they are superior to foreign cardiovascular stents.” He added, “We will do our best to obtain approval for clinical trials of non-polymer drug-eluting stents and focus on domestic production to reduce the economic burden on patients in Korea.”

This content was produced with the assistance of AI translation services.