Chong Kun Dang's 'Bio Spike Guard' Proven to Maintain Sterilization for 24 Hours

Study Results Published in the International Journal of the Korean Society of Infectious Diseases

Chong Kun Dang announced on April 15 that the results of a real-world clinical study on the persistent sterilization effect of its environmental disinfectant wipe 'Bio Spike Guard' have been published in the international journal of the Korean Society of Infectious Diseases, Infection & Chemotherapy.

The study results on the lasting sterilization effect of Chong Kun Dang's 'Bio Spike Guard' were published in the international journal of the Korean Society of Infectious Diseases, Infection & Chemotherapy. Chong Kun Dang

Bio Spike Guard is an environmental disinfectant wipe that combines didecyldimethylammonium chloride (DDAC), which provides immediate sterilization, with organosilane (Si-QAC), which forms a physical protective barrier on surfaces. According to the company, the product is designed to replicate the spike structures found on the wings of fossilized dragonflies—structures that remain preserved without microbial damage—and applies this concept as a protective barrier to maintain sterilization. After immediate sterilization, it leaves a protective film on the surface, which physically eliminates bacteria.

This study was conducted as a real-world, controlled comparative research involving five university hospitals: Seoul St. Mary’s Hospital at The Catholic University of Korea, Asan Medical Center, Seoul National University Bundang Hospital, Konkuk University Medical Center, and Gachon University Gil Medical Center.

The research team compared the effectiveness of Bio Spike Guard against the standard disinfection method in more than 160 locations, including 'dry zones' such as hospital bed rails and nurse stations—areas frequently contaminated by microorganisms—and 'wet zones' such as sinks and toilet lids.

Results showed that Bio Spike Guard maintained a significant reduction in microbial contamination (P<0.001) compared to baseline even after 1 hour, 6 hours, and 24 hours following disinfection. In contrast, the control group, which used the standard hospital disinfection method, did not show a statistically significant sterilization effect, and microbial regrowth occurred over time, failing to maintain the effect.

The company stated that the product demonstrated excellent efficacy in 'wet zones,' where bacterial concentrations are high and management is challenging. In the comparative analysis conducted one hour after disinfection, Bio Spike Guard produced a significantly greater reduction in microorganisms than the control group (P=0.004), underscoring its outstanding infection control performance in high-risk environments.

Professor Noh Deokhee, the first author of the article and an infectious disease specialist at Seoul St. Mary’s Hospital, commented, “This research is significant in that it directly verified the persistent sterilization effect of Bio Spike Guard on various contact surfaces within a real university hospital setting. It is impressive that the product proved effective with a single use even in areas that are difficult to manage for infection control.”

Professor Lee Donggun, the corresponding author and an infectious disease specialist at Seoul St. Mary’s Hospital, stated, “Infection control in clinical settings hinges on maintaining a continuous sterilized state rather than relying on one-time disinfection. The 24-hour persistent effect proven in this study offers a practical alternative for blocking hospital-acquired infections, including multidrug-resistant bacteria.”

A Chong Kun Dang representative stated, “This multi-center clinical study marks an important milestone by demonstrating that the unique, long-lasting sterilization power of Bio Spike Guard is also effective in the demanding environments of real medical settings. We will continue to provide innovative infection control solutions grounded in scientific evidence to create a safer medical environment for both patients and healthcare professionals.”

This content was produced with the assistance of AI translation services.