Busan Sehwa Hospital Infertility Research Institute Unveils Innovative Human Embryo Freezing Technology on the Global Stage

Application of uMAP Technology Reduces Embryonic Cell Apoptosis
Selected as a "Top 10 Poster"

Dr. Hana Park of the Infertility Medicine Research Institute at Busan Sehwa Hospital presented a vitrification freezing technology that improves the thermal conductivity of human embryos at the 14th Pacific Society for Reproductive Medicine (PSRM 2025) held in Kuala Lumpur, Malaysia.

Dr. Hana from the Infertility Medical Research Institute at Busan Sehwa Hospital is presenting the vitrification freezing technology that improves human embryo thermal conductivity at the 14th Pacific Society for Reproductive Medicine (PSRM 2025) held in Kuala Lumpur, Malaysia.

This study introduces an innovative approach to freezing human blastocysts generated during the in vitro fertilization (IVF) process, utilizing an ultra-mini aluminum plate (uMAP, ultra-Mini Aluminum Plate) instead of the conventional Closed Pulled Straw (CPS) method.

The uMAP significantly increases the cooling rate, minimizing the temperature difference inside and outside the cell. This substantially reduces apoptosis (cell death) during the freezing process, thereby improving cell preservation and survival rates.

According to the research findings, the total cell number was significantly higher when using uMAP compared to CPS (216.1 ± 88.3 vs. 152.2 ± 60.7, P<0.05), and the apoptosis rate was also greatly reduced (8.1 ± 4.7% vs. 27.6 ± 14.7%, P<0.05). These results indicate that minimizing structural damage to the blastocyst can contribute to enhanced embryonic developmental capacity and implantation potential.

Dr. Park's research received high recognition from the society, being selected as one of the Top 10 posters and earning a five-minute oral presentation opportunity.

Lee Sangchan, Director of Busan Sehwa Hospital, stated, "This study demonstrates an innovation in the physical heat transfer structure of embryo cryopreservation technology," adding, "We plan to develop this into a next-generation freezing technology suitable for future clinical applications."

The Pacific Society for Reproductive Medicine (PSRM) is the largest international reproductive medicine society in the Asia-Pacific region. This year, under the theme 'Elevating Fertility Care: Innovations and Impact,' more than 1,000 experts participated. Busan Sehwa Hospital aims to lead the advancement of future reproductive medicine technologies through cutting-edge infertility and reproductive medicine research and international academic exchange.

This content was produced with the assistance of AI translation services.