Pukyong National University Researcher Lee Ye-chan Receives 'Best Paper Award' at SPIE International Conference

Researcher Lee Ye-chan, Ph.D. in Biomedical Engineering at the Marine Bionics Convergence Technology Center of Pukyong National University, received the Best Paper Award and a prize of $1,000 at the international conference organized by the International Society for Optics and Photonics (SPIE).

Lee presented his paper titled "Study on Diffuse-Type Optical Fiber-Based Interstitial Photodynamic Therapy Technology for Localized Progressive Prostate Cancer" at SPIE 2023 Photonics West held recently in San Francisco, USA, receiving excellent evaluations.

In his paper, Lee revealed research results on large-area light delivery technology that maximizes the effects of light-based anticancer photodynamic therapy.

In this study, he irradiated light using a diffuse-type optical fiber capable of uniform 360-degree light delivery based on micro-patterning on prostate cancer cells and xenograft animal models. As a result, it was confirmed that the expression of apoptosis-inducing factors in cancer cells was promoted, enabling phototherapy over a wide area.

Researcher Lee Ye-chan (second from the left), Im Seong-hee (first from the left), and master's student Shin Hwa-rang stood in front of the camera.

Lee conducted this research with master's students Lim Seong-hee and Shin Hwa-rang from the Department of Convergence Bionics Engineering of the 4th Industrial Revolution, supported by the National Research Foundation of Korea's Science and Engineering University-Focused Research Center Support Project and the Pan-Government Full-Cycle Medical Device Development Project.

Additionally, he has published 15 papers including six first-author SCI-level papers and registered one patent in areas such as development of light delivery devices for disease-tailored therapy and photobiomodulation research.

Founded in 1955, SPIE is a prestigious global society in the field of optoelectronics engineering, with over 250,000 cumulative members from 183 countries. At this conference, more than 4,500 papers were presented, and 60 awardees including Lee were selected.

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