RF Semi receives patent technology transfer for 'Exosome Isolation Device'... "Accelerating Development"

[Asia Economy Reporter Hyunseok Yoo] RF Semi, a semiconductor manufacturing specialist company, announced on the 16th that it has signed a patent transfer agreement for the 'Exosome (EV) Separation Device' with the Industry-Academic Cooperation Foundation of Kyungpook National University.

RF Semi, together with Professor Moonchang Baek of Kyungpook National University School of Medicine, conducted research for about three years from January 2019 on a small-capacity exosome separation device utilizing semiconductor technology. The company will acquire the patent rights for the jointly developed technology.

Exosomes are vesicles sized 50?200 nm that contain key substances such as proteins, lipids, nucleic acids (mRNA, miRNA), and metabolites, allowing insight into the characteristics and conditions of the cells that secrete them, making them effective for diagnosing and treating various diseases.

Due to their extremely small size, separating exosomes from samples is difficult, and existing common concentration methods require significant cost, time, and labor.

Traditional exosome separation using centrifuges takes several hours for small quantities and several days for large quantities, with the problem of exosome damage. However, the newly developed separation device can isolate exosomes within minutes for small quantities and within hours for large quantities, resolving the damage issue.

This is expected to contribute to accelerating exosome research by rapidly extracting high-purity exosomes. Jin-Hyo Lee, CEO of RF Semi, stated, "Exosomes, which are used in various industries such as therapeutics and cosmetics, have been difficult to separate, resulting in high prices and research challenges. We plan to develop and supply small- and large-capacity exosome separation devices for laboratory use within this year by utilizing the acquired patent rights."

This content was produced with the assistance of AI translation services.