ZennCell, Individual Recognition by MFDS as an Ingredient for Improving Premenstrual Syndrome in Women

Utilization of Native Korean Plants Maek-a and Gujeolcho
Clinical Trials Prove Inhibition of Prolactin Secretion and More

Genensel announced on the 17th that its self-developed natural material complex of malt and Gujeolcho extract, 'Primencia,' has obtained individual recognition as a functional ingredient for improving female premenstrual syndrome (PMS) from the Ministry of Food and Drug Safety.

Genensel developed Primencia through joint research with Kyung Hee University and Dongkook Pharmaceutical, investing about 3 billion KRW over approximately six years since 2017.

The ingredient was recognized by the Ministry of Food and Drug Safety for its functionality with the statement that it "may help improve uncomfortable conditions caused by premenstrual changes."

Through preclinical and human application trials, Genensel demonstrated that Primencia normalizes prolactin (milk hormone) secretion by activating dopamine receptors and inhibits estrogen (female hormone) receptor activation. It was confirmed to have effects such as alleviating premenstrual syndrome symptoms, protecting pituitary cells, and improving uterine inflammation.

Premenstrual syndrome is a condition experienced by more than 30% of women of reproductive age, with symptoms including mild mental disorders, abdominal bloating, weight gain, breast tenderness, muscle tension, decreased concentration, and changes in appetite.

A Genensel official stated, "Since female premenstrual syndrome requires long-term management, consumer demand for health functional foods with excellent efficacy and minimal side effects is continuously increasing." He added, "We expect to receive positive responses in the market by developing safe, high-functional ingredients using domestic native plants."

Genensel has completed domestic patent registration for the ingredient and has filed patents in nine overseas regions including the United States, Europe, Australia, and Japan. The research was selected as a project under the Ministry of Agriculture, Food and Rural Affairs' 'High Value-added Food Technology Development Project' and received development funding support.

This content was produced with the assistance of AI translation services.