Professors Choi Se-young and Jang In-ho of Chung-Ang University Hospital's Department of Urology Awarded 'Best Academic Award' by the Korean Prostate Society
Choi Se-young (left) and Jang In-ho, professors of Urology at Chung-Ang University Hospital.
View original image[Asia Economy Reporter Lee Gwan-joo] Chung-Ang University Hospital announced on the 11th that the urology professors Se-young Choi and In-ho Jang's team received the 'Best Academic Award' at the '30th Annual Meeting of the Korean Prostate Society.'
Professors Se-young Choi and In-ho Jang's team have been conducting joint research with Professor Cheong-soo Kim of Ewha Mokdong Hospital to develop immunotherapeutics for prostate cancer. They presented a paper titled "Immune checkpoint molecules-targeting recombinant dendritic cells for therapeutic effect on prostate cancer," which was selected for this Best Academic Award.
Anti-cancer immunotherapy is a treatment method that uses the ability of our body's immune cells to kill cells to attack cancer cells. To enhance the effect of anti-cancer immunotherapy, it is best to suppress the mechanism by which cancer cells evade our body's immune cells through immune checkpoints as much as possible. While various anti-cancer immunotherapeutics have been developed and shown good treatment outcomes in several cancer types such as lung cancer and colorectal cancer, clear immunotherapeutic effects have not yet been demonstrated in prostate cancer.
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Accordingly, Professor Choi's team announced animal experiment results showing that prostate cancer was suppressed by inserting a gene that inhibits PD-L1 expression into dendritic cells to enhance the effect of anti-cancer immunotherapy. Professor Choi said, "Through this experiment, we were able to confirm the potential of recombinant dendritic cells as an enhanced immunotherapeutic agent for prostate cancer," and added, "We want to develop new treatments for patients suffering from intractable castration-resistant prostate cancer through various basic research."
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