60℃ Hot Air Drying 'Yeongji Mushroom' Treats Atopic Dermatitis

Ganoderic Acid from Yeongji Mushroom Extract
Discovered Skin Inflammatory Disease Treatment Effect
Developed Optimal Extraction Conditions

Asia Economy reporter Hwang Junho] Domestic researchers have developed an extraction technology that can maximize the efficacy of Ganoderma lucidum. By identifying conditions that enhance anti-inflammatory, anti-diabetic, and antioxidant effects, they increased the potential for developing a skin anti-inflammatory treatment. On the 16th, the Korea Institute of Science and Technology announced that the research results presented by Dr. Kim Ho-yeon’s team at the Smart Farm Convergence Research Center, Natural Products Research Institute, Gangneung Branch, were recently published in the international journal Food Chemistry.

Effectiveness Maximized by Hot Air Drying at 60℃

The research team sought methods to reduce the destruction of active ingredients in Ganoderma lucidum and enhance its efficacy. First, to maximize the anti-inflammatory effect, they confirmed that hot air drying at 60℃ was the most effective condition. This is when a large amount of ganoderic acid is extracted. Next, to maximize antioxidant and anti-diabetic activities, they found that freeze-drying at 50℃ was the most effective.

Ganoderma lucidum has been used as a medicinal mushroom in the Northeast Asian region for a long time. The ganoderic acid contained in this mushroom is known to have excellent effects in enhancing cellular immune functions. However, there was a problem where this component could be destroyed depending on the processing method.

Additionally, the research team experimented with hot air dried Ganoderma lucidum extract on skin keratinocytes with induced inflammation and confirmed that it has an effect of suppressing skin inflammation. The extraction condition showing such excellent effects on skin anti-inflammation was recognized as previously undisclosed, leading to a patent application.

Potential Development of Treatments for Psoriasis and Atopic Dermatitis Inflammatory Skin Diseases

The research team expects that these research results can be utilized in developing skin inflammation treatments. Dr. Kim Ho-yeon stated, "Since the efficacy of Ganoderma lucidum varies depending on drying and extraction methods, it is important to appropriately select the drying method according to the intended use." He added, "We expect that this research will not only increase the usability of Ganoderma lucidum but also lead to the development of treatments for inflammatory skin diseases such as psoriasis and atopic dermatitis in the future."

This content was produced with the assistance of AI translation services.