73% Market Share in the Hydroquinone Segment

Donga Pharmaceutical announced on May 20 that its pigmentation treatment, Melatonin Cream, has surpassed cumulative sales of 3 million units in the five years since its launch.


Dong-A Pharmaceutical, Pigmentation Treatment 'Melatonin Cream'. Dong-A Pharmaceutical

Dong-A Pharmaceutical, Pigmentation Treatment 'Melatonin Cream'. Dong-A Pharmaceutical

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Melatonin Cream is a pigmentation treatment containing 2% hydroquinone, introduced by Donga Pharmaceutical in 2021. The main ingredient, hydroquinone, inhibits tyrosinase, an enzyme that promotes melanin production, thereby preventing excessive melanin formation. In addition, it acts on the structure of melanosomes within melanocytes, where melanin is produced, to bleach excessively deposited pigment. According to the company, this dual action helps treat skin hyperpigmentation.


Melatonin Cream features a tube-type package for user convenience. Recently, reflecting consumer demand, a large-capacity 50g version was launched, allowing generous use not only on the face but also on body areas. Donga Pharmaceutical also offers 'Melanosa Cream' containing 4% hydroquinone, providing customized solutions tailored to the severity of pigmentation issues, such as dark spots and age spots.


According to IQVIA Sell-Out Units data, Melatonin Cream has led the market with a share of over 70% in the hydroquinone-based product segment since 2023. In particular, it established itself as a leading pigmentation treatment last year by selling over 1.3 million units in a single year.


Melatonin Cream recently appointed actress Jun Ji-hyun as its model, further strengthening its marketing activities. The current campaign emphasizes the importance of addressing the root causes of pigmentation through over-the-counter medicines and focuses on promoting the efficacy of hydroquinone, its main ingredient.



A representative from Donga Pharmaceutical stated, "Surpassing cumulative sales of 3 million units within five years of launch was made possible by the trust consumers have in our product," adding, "We plan to continue enhancing the product's competitiveness to better support consumers seeking treatment for pigmentation."


This content was produced with the assistance of AI translation services.

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