Inscovery's new drug development subsidiary Apimez announced on the 12th that it has developed a process related to heavy metal reduction and filed a technology patent.


This technology plays a role in removing heavy metals from dioctahedral smectite, the main ingredient used in antidiarrheal and antiperistaltic agents. Previously, antidiarrheal and antiperistaltic agents containing dioctahedral smectite were banned for use in children and pregnant women in 2019 due to the possibility of containing heavy metals such as lead. By utilizing the technology developed by Apimez, these issues can be resolved, and heavy metals in antidiarrheal and antiperistaltic agents can be removed.


Seol Sang-ho, head of research at Inscovery Apimez, explained, “The patented technology removes heavy metals at the highest level among existing raw pharmaceutical ingredients,” adding, “After considering past heavy metal issues, we developed a function to remove heavy metals through acid treatment following heavy metal content analysis.”


Seol further stated, “It was developed by utilizing the raw material’s characteristic of releasing internal substances in low pH environments and adsorbing external substances in high pH environments,” and added, “Above all, it maintains the original adsorption power of the existing ingredient while removing heavy metals.”



Inscovery’s Apimez is a new drug development company that developed ‘Apitoxin,’ a specialized pharmaceutical product and Korea’s first natural new drug (the 6th new drug in Korea). Apitoxin is an osteoarthritis pain and inflammation treatment that can relieve pain through injection prescriptions without surgery. The initial domestic production volume of Apitoxin in 2024 has been completely sold out, with sales continuously increasing, and the company is engaged in developing various new drugs and substances, including heavy metal reduction technology for antidiarrheal agents.


This content was produced with the assistance of AI translation services.

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