Skin Barrier Improved by 50.74%... 'EGF Cream' Now Available at Pharmacies

[2026 Asia Consumer Awards]
Hanmi Science Wins Top Excellence Award

You can now find Hanmi Science’s derma cosmetic brand ‘PRO-CALM’ functional whitening and anti-wrinkle cosmetic, ‘EGF Active Vital Cream,’ at pharmacies.

The key ingredient in this product, Epidermal Growth Factor (EGF), is a human-derived wound-healing protein that helps promote collagen production within cells. It contains 10 ppm, the maximum amount permitted for cosmetics by the Ministry of Food and Drug Safety, helping to fundamentally improve the skin’s foundation. In addition, it provides intensive, highly nourishing care that closely adheres to damaged skin areas through: ▲Okra fruit extract, a plant-based mucin ingredient ▲‘GREENOL H,’ a patented ingredient for skin soothing ▲‘U-OLIOSOME B5,’ a patented ingredient that maximizes the efficacy of panthenol ▲‘TECA-Biome,’ a blend of three types of probiotics and standardized Centella asiatica extract.

In particular, the GREENOL H and U-OLIOSOME B5 ingredients have received the lowest risk ‘green’ rating in the cosmetics ingredient safety assessment conducted by the Environmental Working Group (EWG), a U.S. nonprofit environmental organization. They have also been classified as harmless ingredients by major domestic cosmetic ingredient analysis platforms.

The efficacy of EGF Active Vital Cream has been proven through human application trials. In a two-week skin barrier improvement test on 23 adult women in Korea, the skin barrier was shown to improve by 50.74% after exposure to external irritation. The product received a ‘low irritation’ rating in a skin irritation test conducted by the Korea Institute of Dermatological Sciences, and it also passed the same institute’s eye irritation and sensitive skin tests, confirming its suitability for sensitive skin.