National Institute for Korean Medicine Development Confirms Safety of 'Mangemtang', a Treatment for Cerebrovascular Disease Sequelae

The research team at the Nonclinical Herbal Medicine Trial Center of the National Institute for Korean Medicine Development recently published the results of a nonclinical safety evaluation study on the herbal decoction 'Mangemtang' in the international journal 'Advances in Traditional Medicine'.

Mangemtang is a representative herbal prescription used to treat sequelae of cerebrovascular diseases.

The sequelae of cerebrovascular diseases are among the main conditions included in the Ministry of Health and Welfare's 'Herbal Decoction Health Insurance Pilot Project'. The results of this study are expected to provide scientific evidence to support future discussions on expanding insurance coverage for herbal decoctions and Korean medicine treatments.

This study was conducted in accordance with both domestic and international guidelines, based on Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) standards.

Nonclinical Safety Evaluation Study of 'Mangemtang'. Provided by the National Institute for Korean Medicine Development

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The study items included: ▲analysis of heavy metals and pesticide residues ▲analysis of mycotoxins ▲genotoxicity (such as carcinogenicity, teratogenicity, and genetic damage) ▲and acute toxicity (reactions to excessive dosing) verification.

The study found that Mangemtang met all quality standards for residual pesticides and heavy metal content, and no toxic reactions or carcinogenic potential were observed from excessive dosing.

Hwang Sungmin, a researcher who participated in the study, stated, "Based on these results, I hope to contribute to the advancement of Korean medicine by providing scientific evidence for the efficacy and safety of various areas of Korean medicine, including herbal decoctions, herbal preparations, and applied Korean medicine products."

The Nonclinical Herbal Medicine Trial Center at the National Institute for Korean Medicine Development will continue to secure scientific safety evidence so that the public can safely take herbal medicine, and plans to expand its research fields to support research and development in various industries such as medical devices and cosmetics.

National Institute for Korean Medicine Development Nonclinical Trial Center.

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